Immunopharmacological design of a multi-epitope vaccine targeting hepatitis C virus genotype 3a.
Results indicate that multiple-epitope vaccine constructs have strong binding properties and are good candidates for developing a vaccine against HCV3a.
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Results indicate that multiple-epitope vaccine constructs have strong binding properties and are good candidates for developing a vaccine against HCV3a.
The proposed construct could serve as a potential vaccine candidate for detailed experimental validation towards developing an Mtb-specific vaccine and is encouraging in silico data.
The overall results of the MD showed the overall stability of the NEK2–ligand complexes, and thus these three compounds are promising NEK2 inhibitor candidates and could be further validated in vitro and in vivo for clinical application.
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