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Open access Jul 2026

Kernelized approach enables explainable gene prioritizations for complex traits

K-PoPS provides a post hoc framework for examining and interpreting GWAS effector-gene nominations by decomposing each prediction into contributions from training genes, and identifies multiple plausible effector genes within a dilated cardiomyopathy locus contrary to the parsimonious assumption.

Tao-Tao Tan, M. Samee · 0 citations

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