Author

M. Schaich

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Open access Aug 2026

XRCC1 Enables the Efficient Local Search for DNA Damage by DNA Polymerase Beta

It is demonstrated that XRCC1 reshapes pol β search behavior to promote efficient local damage recognition, providing a mechanistic basis for how BER factors coordinate lesion detection and processing to maintain genomic stability.

Spencer H. Thompson, Kaitlin M. DeHart, M. Schaich et al. · bioRxiv · 0 citations