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M. Senni

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Review Open access Oct 2026

Sex-Based Differences in Chronic Heart Failure: a Systematic Review and Meta-Analysis of Randomized Controlled Trials.

BACKGROUND Sex-based disparities in patient enrollment and treatment effects in heart failure (HF) randomized controlled trials (RCTs) have been reported. We aim to systematically analyze sex-based enrollment and treatment effect differences in HF RCTs over time. METHODS RCTs enrolling patients with chronic HF were s...

L. Fazzini, L. Pascalis, C. Madaudo et al. · 0 citations
Open access Aug 2026

HFpEF-ABA Score and Finerenone in Patients With Heart Failure and Mildly Reduced or Preserved Ejection Fraction: Insights From the FINEARTS-HF Trial.

BACKGROUND The HFpEF-ABA score is a simple diagnostic tool developed to estimate the probability of heart failure with preserved ejection fraction (HFpEF) using age, body mass index, and history of atrial fibrillation. OBJECTIVES This study aims to evaluate the HFpEF-ABA score in patients with confirmed heart failure...

R. Ono, K. Docherty, A. Henderson et al. · 0 citations
Review Open access Aug 2026

Nurse led titration of guideline-directed medical therapy for heart failure: an operative flow chart

Abstract Background and Aims Titration of guideline-directed medical therapy (GDMT) in heart failure (HF) is recommended by current guidelines. Recent data show that titration is not performed in most patients because of barriers related to healthcare systems, patient factors, and therapeutic inertia, leading to worse...

M. Gori, M. Barisone, R. De Maria et al. · 0 citations
Open access Sep 2026

Efficacy of Vericiguat by Background Guideline-Directed Medical Therapy in the VICTOR Trial.

In ambulatory patients with HFrEF receiving contemporary GDMT, it is not convincing evidence that the neutral effect of vericiguat on cardiovascular death or first HF hospitalization was modified by GDMT class, dose attainment, or overall intensity, in a cohort with very high background GDMT use and limited power for i...

Justin A. Ezekowitz, J. Butler, Derek Cyr et al. · 0 citations
Aug 2026

Diagnostic Value of Calcium Score Derived From Virtual Noncontrast, Non-ECG-gated Dual-energy CT as an Indicator of Severe Aortic Stenosis.

Aortic Valve Calcium Score obtained on VNC images from DECT examinations is a promising method for noninvasively differentiation between severe and nonsevere aortic stenosis, which could be potentially useful in patients who have undergone examinations for noncardiac indications.

Jakub Byczkowski, Gregorio Chierchia, G. Muscogiuri et al. · 0 citations

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