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M. Sharp

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Open access Oct 2026

Shared and distinct effects of cognitive performance and mood on cognition-dependent instrumental activities of daily living in Parkinson disease

Background: Cognitive impairment in Parkinson disease (PD) significantly affects patients ability to perform instrumental activities of daily living (IADLs). However, neuropsychiatric symptoms, which are highly prevalent in PD, may also contribute to functional impairments. In this study, we investigated the independen...

J.-Y. Hu, S. Sun, M. Sharp · 0 citations
Open access Jul 2026

Nucleus basalis of Meynert integrity is associated with cognitive dysfunction in Parkinson's disease independently of locus coeruleus degeneration

It is suggested that in early-stage PD, nbM microstructural changes may account for unique variance in executive dysfunction in PD, independent of the effects of LC degeneration, and with a stronger association in PD than controls.

A. Bailey, E. St-Onge, V. Madge et al. · 0 citations

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