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Open access Sep 2026

Integrative Multi-Omics and Structure-based Analysis of DHODH Reveals its Therapeutic Potential in Colorectal Cancer

Dihydroorotate dehydrogenase (DHODH) is a mitochondrial enzyme involved in de novo pyrimidine biosynthesis and has emerged as a potential target in cancer metabolism and therapy. This study integrated transcriptomic analysis with structure-based drug discovery to investigate the biological significance and therapeutic...

M. Sheikh, Md. Shahidul Islam, Manuocher Shakib et al. · 0 citations
Aug 2026

Phytochemical characterization, pharmacological activities, and in silico analysis of the methanolic extract of reishi mushroom (Ganoderma lucidum).

ETHNOPHARMACOLOGICAL RELEVANCE Medicinal plants are widely used in traditional medicine to treat various diseases, especially in communities with limited access to conventional healthcare. Ganoderma lucidum (Reishi mushroom) is a medicinal fungus that has been widely used in traditional medicine systems, particularly i...

Mst Soheli Akhter Nifa, M. Abdullah, Monirul Islam et al. · 2 citations

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