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Author

M. Sherlock

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2 papers indexed here

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Open access Aug 2026

A structural bridge between dengue virus tandem xrRNAs facilitates coordination of exonuclease resistance

ABSTRACT Orthoflavivirus RNA genomes resist host 5′–3′ exoribonucleases to produce subgenomic flaviviral RNAs (sfRNAs). This resistance is conferred by exoribonuclease-resistant RNA (xrRNA) structures within the viral 3′ untranslated region that often occur in tandem, and whose function can be coupled. In dengue virus...

Elizabeth A. Spear, Z. O’Donoghue, Steve L. Bonilla et al. · 0 citations
Sep 2026

Enterovirus RNase L inhibiting RNAs are highly conserved with limited phylogenetic distribution.

RNA molecules form specific 3D structures that facilitate a variety of functions through interactions with other macromolecules. Many RNA viral genomes maintain these structures to interact with and evade host immunity machinery. One such element, the competitive inhibitor RNA (ciRNA), discovered in the protein coding...

Samantha I. Zangari, M. Sherlock, Jeffrey S. Kieft · 0 citations

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