Background Deficits in inhibitory control are considered a central feature of alcohol use disorder (AUD), yet behavioral and neuroimaging findings have been inconsistent. One potential explanation is the marked heterogeneity of AUD, which encompasses multiple symptom dimensions that may differ in their underlying neuro...
J. Böhmer, Pablo Reinhardt, Marco Bottino et al.· bioRxiv· 0 citations
The translation of abstract cognitive intention into localised physical action is a defining feature of voluntary behaviour1,2. To achieve this, the brain must maintain a highly regulated preparatory state, yet the macroscopic architecture of this interface remains elusive. Historically, the primary motor cortex has be...
Chen Zheng, Shi-Tong Xiang, Chao Xie et al.· Research Square· 0 citations
It is found that smartphone-based, gamified tasks show promise to identify periods of heightened risk paving the way for mechanism-based, real-time interventions in AUD: specific decision-making alterations precede changes in consumption.
Hilmar Zech, Maria Waltmann, D. Reichert et al.· Biological Psychiatry: Cogni...· 0 citations
Early detection and prevention of psychiatric disorders, particularly depression, remain as major global health challenges, yet reliable tools for identifying individuals before symptom onset are lacking. Here, we combine functional neuroimaging with computational modeling to identify a mechanistic biomarker of depress...
Han Lu, Xiaoqian Yan, Benjamin Becker et al.· Science Advances· 0 citations
It is demonstrated that different environments generate distinct biological associations with brain maturation, which underscores the need to consider both grey and white matter when assessing the neurodevelopmental pathways to outcomes across the lifespan.
Lea C. Michel, D. Rakesh, T. Banaschewski et al.· bioRxiv· 0 citations
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