Author

M. Sonbol

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Open access Aug 2026

Phase 2 study of futibatinib in combination with pembrolizumab in patients with FGF19 expressing advanced hepatocellular carcinoma

Abstract Introduction Optimal treatment following first-line immunotherapy for advanced hepatocellular carcinoma (HCC) remains uncertain. This study evaluated futibatinib, a pan-FGFR inhibitor, combined with pembrolizumab in previously treated patients with FGF19-expressing HCC. Methods Eligible patients were ≥18 years...

Nguyen H. Tran, M. Palmer, Angela Ulrich et al. · The Oncologist · 0 citations

Review Open access 2026

Biomarker-Driven Precision Oncology in Advanced Gastroesophageal Adenocarcinoma: Current Standards and Future Directions

: Advanced gastroesophageal adenocarcinomas (GEA) have undergone a major therapeutic shift from empiric chemotherapy toward biomarker-driven precision oncology. Routine incorporation of immunohistochemistry (IHC), in situ hybridization, next-generation sequencing (NGS), and liquid biopsy have enabled identification of...

Fares Jamal, Abdullah Alsulaiman, Oudai Sahwan et al. · Oncology Research · 0 citations

Open access Sep 2026

Colon cancer in a patient with a mosaic monoallelic germline pathogenic NF1 gene variant

Pathogenic variants in the tumor suppressor gene NF1 cause neurofibromatosis type 1 (NF1), one of the most common hereditary cancer predisposition syndromes. Pathogenic NF1 variants have been associated with an increased risk of several cancers; however, the relationship between NF1 variation and colon cancer remains u...

Feras Alsabagh, Karam M. Chaaban, M. Girardo et al. · Exploration of Neuroscience · 0 citations