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Review Open access Aug 2026

A practical application for the efficient use of historical data in randomized controlled design using systematic review data.

INTRODUCTION Randomized controlled trials are the gold standard for evaluating interventions but are resource-intensive and impose considerable burden on participants. Historical control designs, which incorporate data from previous trials into new analyses, could reduce sample size requirements, but their practical ap...

Tim J. Schouten, A. Gabrio, Jochen W L Cals et al. · 0 citations
Open access Jan 2026

Tuberculosis Incidence and Predictors Among People Living With HIV After Isoniazid–Rifapentine (3HP) Preventive Therapy in Ethiopia: A Retrospective Cohort Study

Background Global reports of tuberculosis (TB) in 2024 estimated 10.7 million cases, of which 5.8% were HIV‐positive individuals. Despite the implementation of TB preventive therapy, TB incidence rates remain high, especially among HIV‐infected patients. Methods A retrospective cohort study was conducted from 1 October...

E. Etu, Edao Wajiso Kallo, Kelil Husen Lenbo et al. · 0 citations

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