Open access
Oct 2026
Association between up-titration of guideline-directed medical therapy and clinical outcomes in patients with chronic heart failure with reduced ejection fraction
In patients with HFrEF, up-titration of GDMT was independently associated with favourable clinical outcomes and LVRR, and the GDMT score could facilitate optimisation of GDMT even in patients with chronic HFrEF.
Y. Agata, T. Nagai, T. Tamura et al.
· European Heart Journal · 0 citations