Recombinant Annexin A5 Alleviates Aluminum Chloride-Induced Cytotoxicity, Mitochondrial Dysfunction, and Apoptotic Signaling in SH-SY5Y Cells
Background: Aluminum contributes to neurodegeneration by inducing oxidative stress, disrupting mitochondrial membrane potential (MMP), and triggering apoptotic signaling cascades. Annexin A5 (ANXA5) is implicated in membrane repair, ion transport regulation, and neuroprotection. This study aimed to evaluate whether ANX...