Structural connectomics provides a means of characterising white matter (WM) network organisation using diffusion MRI (dMRI), but reconstructing neonatal structural connectomes remains challenging due to the immature and heterogeneous nature of the developing brain. Although recent neonatal studies have increasingly ad...
C. K. W. Hew, S. Leserri, D. Aydoğan et al.· medRxiv· 0 citations
Preterm birth is strongly linked to systemic inflammation and encephalopathy of prematurity, which underlies subsequent cognitive impairment. T-cell immunity contributes to brain-immune crosstalk across the life course but its role in the pathogenesis of encephalopathy of prematurity is unknown. Protein epigenetic scor...
R. Smikle-Bernard, M. B. Cabez, K. Vaher et al.· medRxiv· 0 citations
Diffuse gliomas, the most common adult primary brain tumour, are classified by their histological, genetic, and molecular characteristics. Isocitrate dehydrogenase (IDH) mutations correlate with longer mean survival and progression-free survival time. IDH mutations lead to tumour metabolic changes and the product...
M. Thrippleton, P. Brennan, Imran Liaquat et al.· Neuro-Oncology· 0 citations
Background and Objectives Cross-sectional studies suggest that retinal microvascular abnormalities measured by optical coherence tomography angiography (OCTA) are associated with cerebral small vessel disease (cSVD) and cognitive impairment, but longitudinal relationships remain unclear. We investigated whether OCTA me...
Samuel Gibbon, Ylenia Giarratano, Charlene Hamid et al.· Neurology· 0 citations
WMH burden followed an exponential trajectory across Fazekas scores, with population-dependent progression, facilitating cross-study comparison, large-scale epidemiology, and might facilitate clinical decision-making in cerebral small vessel disease.
Yu-Yuan Xu, Francesca M. Chappell, Maria D. Valdes-Hernandez et al.· Stroke· 0 citations
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