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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

M. Toma

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Open access Oct 2026

Establishment of Uveal Melanoma Patient-Derived Organoids Using an Air–Liquid Interface System for Translational Research

Purpose Uveal melanoma (UM) is the most common primary intraocular malignancy in adults, with a unique genetic and epigenetic profile and a high metastatic risk. The lack of experimental models to replicate tumor biology, including its epigenetic landscape, limits progress in translational research. Recently, patient-d...

Leticia Ussem, Karin U. Loeffler, Verena Tischler et al. · 0 citations
Open access Aug 2026

AI-enabled discovery and biochemical optimization of minibinders targeting cancer cell-surface proteins

This work presents a scalable mammalian cell-display workflow to identify AI-designed minibinders against cancer surface targets and identifies biochemical optimization beyond the binding interface as a critical requirement for translating AI-minibinders into functional applications.

B. Broske, B. McEnroe, S. C. Frechen et al. · 1 citation

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