Background and Objectives: Anatomical variations in the Circle of Willis (CoW) may influence cerebral collateral pathways and the interpretation of vascular imaging. This study characterized their prevalence and clinical associations in a Turkish computed tomography angiography (CTA) cohort using complementary patient-...
Bekir Sıtkı Said Ulusoy, D. Aslan, Ahmet Burak Kara et al.· Medicina· 0 citations
Background/Objectives: Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype with limited targeted therapeutic options. Although the anticancer and pro-apoptotic properties of boswellic acids have previously been reported, the interaction profile of chemically defined β-boswellic acid (BA) with do...
Z. Küçük, M. Tuncer, Ş. Öztürk· Biomedicines· 0 citations
Overall, EGCG and DOX exhibited synergistic interactions and multiple treatment-associated cellular and transcriptional responses in HeLa cells under the present in vitro conditions, which provide a basis for validation in additional cervical cancer models and at clinically relevant exposures.
Mehmet Emin Ayağ, M. Tuncer, Ş. Öztürk· Biomolecules· 0 citations
It is suggested that RA may enhance the anticancer activity of Gem in ovarian cancer cells through mechanisms associated with oxidative stress, apoptosis, and proliferation-related signaling pathways under both monolayer and 3D culture conditions.
Coşkun Orhaner, M. Tuncer, İ. Özdemir· International Journal of Mol...· 0 citations
The TQ + DTX combination demonstrated synergistic cytotoxicity and significantly increased apoptotic cell death compared with either monotherapy, providing evidence supporting further preclinical investigation of the TQ + DTX combination as a promising therapeutic strategy for triple-negative breast cancer.
Aylin Orhaner, M. Tuncer, İ. Özdemir· Pharmaceuticals· 0 citations
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