Author

M. van Nimwegen

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Open access Oct 2026

Peripheral blood innate lymphoid cell profiles of patients with COPD reflect their clinical phenotype as identified by cluster analysis

Abstract Introduction Chronic obstructive pulmonary disease (COPD) has a heterogeneous clinical and immunological presentation. Although proportions of group 1 innate lymphoid cells (ILC1) in peripheral blood were shown to correlate with COPD severity, no analysis of ILC subsets in relation to clinical outcomes has bee...

Cathelijne M. van Zelst, Johannes In 't Veen, M. D. de Bruijn et al. · BMJ Open Respiratory Researc... · 0 citations

Open access Sep 2026

PLA2G2D in tumour-draining lymph nodes regulates anti-tumour immunity

In-depth spatial profiling identifies PLA2G2D as a TDLN-centred targetable immune checkpoint for cancer immunotherapy and identifies a specific population of macrophages that express high levels of the enzyme PLA2G2D in tumour-draining lymph nodes that is associated with poor prognosis in patients.

A. van Krimpen, Julie Y. Huang, Mike Eterman et al. · Nature · 0 citations