Open access
Jul 2026
Evaluating exon skipping in the central nervous system in Duchenne muscular dystrophy using spatial transcriptomics
Summary Duchenne muscular dystrophy (DMD) causes progressive muscle degeneration due to dystrophin deficiency. Dystrophin is also expressed in the brain during development and postnatally, yet a characterization of dystrophin isoform expression across brain cells and regions is lacking, limiting our understanding of th...
Qirong Mao, A. Ahmadi, Sharon I. de Vries et al.
· iScience · 0 citations