Clone-by-Clone Therapy Guidance in Luminal Breast Cancer via Spatial Proteomics and Patient-Derived Tumoroid.
Breast cancer (BC) remains the leading cause of cancer-related death among women worldwide, with 2.26 million new cases and ∼685,000 deaths reported in 2020 (Globocan 2020). A major challenge in treating BC, particularly luminal subtypes, is the pronounced molecular heterogeneity both between patients and within indivi...