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M. Vermeulen

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Open access Aug 2026

From stem cells to somites: Revealing genetic and exogenous factors of human embryogenesis

It is shown that pre-differentiation culture medium impacts the developmental potential of induced pluripotent stem cells (iPSCs), with StemFit medium and Matrigel embedding outperforming mTeSR Plus medium in generating robust somite-like structures.

Maria Teresa Alejo-Vinogradova, Y. E. Strøm, L. Lamers et al. · 1 citation
Open access Sep 2026

Methylome profiling of SetDB1-deficient ESCs reveals coordinated epigenetic cross-talk during pluripotency.

SetDB1 is best known for catalyzing H3K9me3, but it also influences H3K27me3 deposition, CTCF-binding, and DNA methylation (DNAme). Given the interplay between DNAme and the other epigenetic features, we profiled DNAme following Setdb1 knockout (KO) in ground-state and serum-grown mouse embryonic stem cells (ESCs) to i...

Nick G. P. Bovee, E. Habibi, Zi-Cong Liu et al. · 0 citations
Review Open access Aug 2026

Protein landscape of the chromatin domains in the malaria parasite Plasmodium falciparum.

A systematic proteomic characterization of the chromatin domains in P. falciparum, an ancient human pathogen with a unique genome composition and epigenetic blueprint, offers a reference proteome of the chromatin domains and a resource to uncover novel chromatin biology.

Gala Ramón-Zamorano, Sheila Mainye, Jessica Kimmel et al. · 0 citations

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