It is shown that pre-differentiation culture medium impacts the developmental potential of induced pluripotent stem cells (iPSCs), with StemFit medium and Matrigel embedding outperforming mTeSR Plus medium in generating robust somite-like structures.
Maria Teresa Alejo-Vinogradova, Y. E. Strøm, L. Lamers et al.· Stem Cell Reports· 1 citation
SetDB1 is best known for catalyzing H3K9me3, but it also influences H3K27me3 deposition, CTCF-binding, and DNA methylation (DNAme). Given the interplay between DNAme and the other epigenetic features, we profiled DNAme following Setdb1 knockout (KO) in ground-state and serum-grown mouse embryonic stem cells (ESCs) to i...
Nick G. P. Bovee, E. Habibi, Zi-Cong Liu et al.· Stem Cell Reports· 0 citations
A systematic proteomic characterization of the chromatin domains in P. falciparum, an ancient human pathogen with a unique genome composition and epigenetic blueprint, offers a reference proteome of the chromatin domains and a resource to uncover novel chromatin biology.
Gala Ramón-Zamorano, Sheila Mainye, Jessica Kimmel et al.· Cell Host and Microbe· 0 citations
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