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Author

M. Vijayabaskar

2 papers indexed here

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Open access Sep 2026

A step-wise, deterministic and fatal mouse model of myeloid neoplasm with spontaneous acquisition of patient-relevant RTK-RAS mutations.

Leukaemia arises through the stepwise transformation of healthy haematopoietic cells, yet the asymptomatic premalignant phase and its progression to overt disease remain poorly understood. To model this process, we engineered a patient-derived CEBPA mutation into Hoxb8-FL multipotent murine progenitors and transplanted...

Marija A. Zarocsinceva, Moosa Qureshi, Nicola K. Wilson et al. · 0 citations
Open access Aug 2026

Multi-scale modeling of human tissues from spatial transcriptomics with TERRA

Spatial transcriptomics maps gene expression at cellular resolution, revealing how cells organize into multicellular niches. Yet computational analyses remain dataset-specific, without a transferable representation of tissue organization that generalizes across datasets, tasks and tissues or predicts how tissues behave...

Sebastian Birk, M. V. Sanian, Amirhossein Vahidi et al. · 4 citations · ⚡1

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