Author

M. von Scheidt

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Open access Oct 2026

Intraindividual longitudinal changes of the proteome reveal dynamic markers of biological aging

Proteomic aging clocks have emerged as biomarkers of aging, but most rely on cross-sectional data. Here, we present a proteomic aging clock based on longitudinal measurements of liquid chromatography–mass spectrometry plasma proteomics at up to three time points in the population-based KORA cohort, comprising 9,105 sam...

R. Lermer, X. Qian, S. Pusch et al. · bioRxiv · 0 citations

Review Open access Sep 2026

Percutaneous left atrial appendage occlusion versus oral anticoagulation in patients with atrial fibrillation: a systematic review and meta-analysis.

INTRODUCTION AND OBJECTIVES Percutaneous left atrial appendage occlusion (LAAO) has emerged as an alternative to oral anticoagulants (OACs) in patients with atrial fibrillation (AF). However, up-to-date comparisons are lacking. We performed a systematic review and meta-analysis of randomized clinical trials comparing p...

M. I. Molaro, Cajetan Reichardt, Fiorenzo Simonetti et al. · Revista Española de Cardiolo... · 0 citations