Review
Open access
Oct 2026
The Role of Sodium Valproate in Clozapine-Associated Cardiotoxicities: The Importance of Cellular and Systemic Energetics
The antipsychotic drug clozapine is associated with one of the broadest spectra of cardiac adverse effects. Many of these are of unknown aetiology, hindering clinicians’ ability to prevent, diagnose, and treat them. Risk factors for clozapine-associated cardiotoxicities include concomitant valproic acid therapy and com...
A. Groenewald, A. S. Power, Kathryn E. Burns et al.
· Cardiovascular Toxicology · 0 citations