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Open access Sep 2026

851. A mechanism for PHF21B recognition of H3K36me3

A specific protein domain that could serve as a therapeutic target for Phelan-McDermid syndrome is defined, and the PHD-zinc finger domain of PHF21B is necessary for its interaction with H3K36me3, and the C-terminal region is dispensable.

M. Wong, Q. Ma, J. Licinio · 0 citations

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