Author

M. Y. Rincon

2 papers indexed here

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Review Open access Sep 2026

Global seroprevalence of neutralizing and total antibodies against AAV vectors and their impact on the clinical gene therapy landscape: a scoping review

Pre-existing neutralizing antibodies (NAbs) and total antibodies (TAbs) against adeno-associated virus (AAV) vectors represent a major barrier to the clinical translation of AAV-based gene therapies. A comprehensive characterization of their global prevalence, determinants, and clinical implications is currently lackin...

Cristina Sánchez Gutierrez, Luisa Fernanda Bohorquez-Zambrano, Camila Garnica-Álvarez et al. · Frontiers in Medicine · 0 citations

Review Oct 2026

Reframing liver test abnormalities after AAV gene therapy: a mechanistic diagnostic framework.

Hepatotoxicity remains one of the most frequent and clinically important safety concerns in adeno-associated virus (AAV) gene therapy. Yet the laboratory patterns observed after vector administration are biologically complex and often difficult to interpret. Alanine aminotransferase (ALT) and aspartate aminotransferase...

B. Henry, B. Bénichou, M. Y. Rincon et al. · Clinical Biochemistry · 0 citations