Open access
Sep 2026
Harmine Plus Exendin-4 Enhances Remission of Recent-Onset Type 1 Diabetes Following Anti-CD3 Therapy
Type 1 diabetes (T1D) results from autoimmune destruction of pancreatic β-cells. While anti-CD3 therapy can delay disease progression and preserve residual β-cell function, disease reversal will likely require both immune modulation and β-cell regeneration. We found that the combination of harmine and exendin-4 (H+E) r...
Ge-Ming Lu, Randy B. Kang, Miguel A. Varela et al.
· bioRxiv · 0 citations