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Author

Magda Bujnowska

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Open access Sep 2026

Mechanistic modeling reveals a configurable AP-1 network governing cell-state heterogeneity and adaptive plasticity in melanoma cells.

AP-1 transcription factors have been implicated in cellular plasticity, differentiation-state heterogeneity, and phenotype switching, enabling adaptation to anti-cancer therapies. Although AP-1 states, defined by the combinatorial expression of AP-1 proteins, are heterogeneous within cell populations, only a subset of...

Yonatan N. Degefu, Magda Bujnowska, Douglas G. Baumann et al. · 0 citations
Review Open access Aug 2026

G-quadruplex structures as regulators of cellular processes and drivers of genome instability in cancer.

Therapeutically targeting G4s requires balancing their essential regulatory roles with their pathological effects, and understanding this tension is essential for exploiting G4s as therapeutic targets across cancer types.

Anna R. Bartosik, Magda Bujnowska, D. B. Stovall et al. · 0 citations

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