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Author

Mahmoud Emam

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Oct 2026

SMILES-Based Deep Learning Enables Discovery of Chemically Modified Ultrashort Antimicrobial Peptides

Sequence-based models for antimicrobial peptides are limited in representing chemically modified peptides, restricting computational discovery to canonical amino acids. Here, we developed SMAMP, a SMILES-based graph deep learning framework that encodes peptides as molecular graphs and captures noncanonical residues a...

Gang Hu, Piao-Ru Wu, Meng-Xi Li et al. · 0 citations

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