Review
Open access
Oct 2026
Engineering phage therapeutics with intrinsic biocontainment.
This work evaluates emerging biocontainment strategies for therapeutic phages and proposes a framework for assessing trade-offs between biocontainment stringency, evolutionary robustness against escape mutants, therapeutic efficacy, and translational feasibility.
Maisie R. Czernuszka, Stefan A. Hoffmann, M. Brockhurst et al.
· Trends in Biotechnology · 0 citations