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Open access Jul 2026

Enhanced Brain Tumor Detection and Classification Using Transfer Learning and Explainable AI with Clinical Report Generator

Correctly sorting brain tumors captured through Magnetic Resonance Imaging (MRI) plays a vital role in timely diagnosis and sound clinical decision-making, since a delayed or wrong call can seriously harm patient outcomes. This work introduces AMC-NeuroDx, an upgraded deep-learning pipeline that pits a Custom Convolutional Neural Network (CNN) built from the ground up against a ResNet50 transfer-learning model on a four-way brain tumor classification task (Glioma, Meningioma, Pituitary Tumor, and No Tumor), drawing on 7,223 MRI scans taken from the Kaggle Brain Tumor MRI dataset. ResNet50 follows a two-stage routine—training with a frozen base before full fine-tuning—and reaches 93.16% validation accuracy after only 20 epochs, whereas the Custom CNN needs 50 epochs to hit 90.70%. The framework also embeds Grad-CAM so that spatial heatmaps can show which brain regions drove each prediction, meeting the clinical demand for transparency. On top of this, a Streamlit interface lets users upload MRI scans in real time and automatically produces patient-specific PDF clinical reports holding the diagnosis, confidence scores, Grad-CAM overlays, and recommended next steps. The results obtained here show that transfer learning yields higher accuracy and quicker convergence than building a CNN from the ground up, and together with the built-in explainability and automated report writing, this makes AMC-NeuroDx a practical candidate for real clinical settings.

Kavya R, Mala M · 0 citations