Author

Malte Brammerloh

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Open access Oct 2026

Validating the neurite exchange imaging (NEXI) model of gray matter using Monte Carlo simulations in numerical substrates

Abstract NEXI is a gray matter (GM) microstructural model designed to probe brain tissue microstructure in vivo using diffusion MRI. NEXI describes GM as two exchanging Gaussian compartments—neurites, modeled as randomly oriented, infinitely long sticks, and the extracellular space—allowing the estimation of biophysica...

R. Oliveira, Jasmine Nguyen-Duc, Malte Brammerloh et al. · Imaging neuroscience · 0 citations

Open access Sep 2026

Selective nigrosome vulnerability in Parkinson’s disease revealed by histology-anchored ultra-high-field quantitative MRI

Selective vulnerability is a hallmark of Parkinson’s disease (PD): post-mortem, dopamine-containing cell loss in the substantia nigra first and most severely affects calbindin-poor compartments termed nigrosomes. Testing this in vivo has been limited by circularity, as MRI studies have delineated nigrosomes from the sa...

Rui-Yi Li, E. Kirilina, PL Bazin et al. · bioRxiv · 0 citations