RNA G‐Quadruplex–Mediated Solubilization and Photodynamic Activation of Protoporphyrin IX
Protoporphyrin IX (PpIX) is a key endogenous photosensitizer used in photodynamic diagnosis (PDD) and photodynamic therapy (PDT); however, its poor aqueous solubility and strong aggregation markedly suppress fluorescence emission and singlet oxygen ( 1 O 2 ) generation. The mechanisms by which PpIX is solubilized...