Author

Manish Pathak

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Review Aug 2026

Targeting BRAF dimerization in cancer: structural insights and therapeutic strategies beyond monomer inhibition.

The mitogen-activated protein kinase (MAPK) signaling pathway is a central oncogenic signaling axis, with BRAF functioning as a critical regulatory node. The discovery of oncogenic BRAF mutations, most notably BRAFV600E, enabled the development of targeted therapies that significantly improved clinical outcomes in seve...

Jayhind Bharti, Priyadharshini Gogu, Dhanashree N. Sarwan et al. · Biochemical Pharmacology · 0 citations

Review Open access Sep 2026

Comparative Ethnopharmacological Insights Into Anti-Inflammatory Phytochemicals From Indian and Chinese Medicinal Plants in the Management of Rheumatoid Arthritis

Medicinal plants from Indian and Chinese systems offer potential as supportive agents in RA management and additional research should concentrate on the aspects of standardization, mechanistic studies and clinical validation to confirm their therapeutic benefits and their safe use alongside other traditional therapies.

Manish Pathak, Akanchha Dwivedi, Sokindra Kumar · Clinical Medicine Insights:... · 0 citations

Aug 2026

Development of novel Schiff Base-triazole hybrids with potent antimicrobial agent: Design, synthesis, in-silico and biological evaluation.

Findings position Schiff-base triazole hybrids as structurally versatile and biologically promising scaffolds, warranting accelerated pharmacological exploration toward the development of next-generation antimicrobial therapeutics.

Javed Khan, Anjali Rani, Mohd Aslam et al. · Bioorganic chemistry (Print) · 0 citations