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Author

Mantas Žiaunys

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2 papers indexed here

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Oct 2026

Effect of freeze-thaw cycle induced oligomers on alpha-synuclein liquid-liquid phase separation and aggregation.

Protein aggregation in the form of amyloid fibrils is linked with the onset and progression of several widespread and incurable disorders, including neurodegenerative Alzheimer's and Parkinson's diseases. Despite decades of research and countless attempts to discover potential aggregation-altering treatment modalities,...

Kamilė Mikalauskaitė, Dominykas Veiveris, V. Smirnovas et al. · 0 citations
Open access Aug 2026

Revealing alkali ion modulation on the nucleation phase of highly concentrated α-synuclein probed by Thioflavin T lasing spectroscopy

Early nucleation events during α-synuclein (αS) aggregation remain challenging to investigate because conventional fluorescence assays lose sensitivity in highly concentrated biomolecular environments. Here, we present Thioflavin T (ThT) lasing spectroscopy in a Fabry–Pérot microcavity as a sensitive methodological app...

K. Struniawski, E. Jałonicka, A. Konopka et al. · 0 citations

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