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Manu Deeudom

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Open access Sep 2026

Computational Investigation of S781F Mutation-Induced Remodeling of the Staphylococcal Nuclease Domain-Containing Protein 1–Argonaute 2 Interface

MicroRNA (miRNA)-guided gene silencing depends on the accurate assembly and regulation of the RNA-induced silencing complex (RISC), in which Argonaute-2 (Ago2) interacts with accessory proteins to facilitate complex stability and catalytic activity. Staphylococcal nuclease domain-containing protein 1 (SND1) is an impor...

Jittasak Khowsathit, Yuvaraj Ravikumar, Manu Deeudom et al. · 0 citations

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