Author

Manuel Weber

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Clinical trial Open access Sep 2026

Neoadjuvant combined immunotherapy with intratumoral TransCon TLR7/8 Agonist and systemic TransCon IL-2 β/y or pembrolizumab in patients with locally advanced oral cancer—a monocentric experience

Combination immunotherapy has shown encouraging activity across multiple solid tumors. We report the complete and consecutive cohort of patients with locally advanced oral squamous cell carcinoma (OSCC) treated at a single center within the prospective, multicenter, randomized phase 2 BelieveIT-201 trial (ASND0038), ev...

Manuel Weber, Leah Trumet, F. Lange et al. · Cancer Immunology and Immuno... · 0 citations

Review Open access Sep 2026

C-type lectin receptors: bone remodeling and therapeutic potential

Osteoimmunology explores the interplay between the skeletal system and the immune system. It focuses on the identification of shared signaling pathways and the mechanisms of mutual regulation. Bone homeostasis depends on the balance between the activity of bone-forming osteoblasts and bone-resorbing osteoclasts. Intere...

Marina Kleim, Aline Bozec, Manuel Weber et al. · Bone Research · 0 citations