Abstract A001: Improved Modeling of Pancreatic Ductal Adenocarcinoma (PDAC) Using High-Density Collagen Matrix
Pancreatic Ductal Adenocarcinoma (PDAC) has a tumor microenvironment (TME) that is rich in organized strands of type I collagen. The most commonly used PDAC models utilize basement membrane extract (BME, e.g. Matrigel), which instead contains the more pliable type IV collagen. We hypothesize that utilizing a high...