Author

Marcel Schmiel

2 papers indexed here

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Open access Sep 2026

γδ T cells modulate anti-tumor immunity in small cell lung cancer.

Small cell lung cancer (SCLC) is a highly aggressive neoplasm with limited sensitivity to anti-PD-(L)1 blockade, which is likely caused by the epigenetic silencing of MHC-I. Elucidating MHC-I-independent immune recognition mechanisms is therefore crucial for enhancing treatment responses and improving clinical outcomes...

Jin Ng, Yue You, Tina Zhang et al. · Cancer Cell · 0 citations

Open access Aug 2026

A targetable dependency on nonsense-mediated decay for cellular homeostasis and immune control in small cell lung cancer

Small cell lung cancer (SCLC) is one of the most aggressive malignancies, characterized by rapid metastatic dissemination and poor overall survival. Despite harboring excessive alterations, expectedly resulting in immunogenic neoantigens, patients with SCLC remain largely refractory to immunotherapy. We found abundant...

Lucia A. Torres-Fernández, V. Boehm, Joel Kaufmann et al. · Molecular Cancer · 0 citations