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Author

Marcia B. Goldberg

2 papers indexed here

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Jul 2026

Human NLRC4 and CASP4 inflammasomes activate GSDMD-mediated killing of S. flexneri independently of macrophage pyroptosis and bacterial cardiolipin 2254736

Elimination of the infecting pathogen is a core function of the immune system. Macrophages are a crucial component of innate immunity against bacterial infections as they internalize and kill intracellular bacteria. Although macrophage restriction of some intracellular bacteria depends on inflammasomes, the speci...

Mateusz Szczerba, María Luisa Gil-Marqués, Marcia B. Goldberg · 0 citations
Open access Jul 2026

A multimodal atlas of COVID-19 severity identifies hallmarks of dysregulated immunity 2258066

The alpha-variant wave of the COVID-19 pandemic provided a unique opportunity to study, at single-cell resolution, how near-universal exposure to the same pathogen can lead to either effective or dysfunctional immune responses in humans. We analyzed 2.5 million circulating immune cells from 428 patients ac...

Kamil Slowikowski, Pritha Sen, C. Cosgriff et al. · 0 citations

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