Autoimmune diseases are very common worldwide. The immune system becomes dysregulated in a pro-inflammatory direction. Bromodomains play a crucial role in the regulation of many inflammatory pathways, including mitogen-activated protein kinase, nuclear factor kappa B, and interleukins. Bromodomain inhibitors could allo...
Marcin Szczepanik, Wojciech Pociej, Joanna Kulpa et al.· Immunotherapy· 0 citations
A thorough analysis of ADC possibilities in oncology focusing on treatment options, side effects of therapies for breast, bladder and lung cancers reveals ADC to be a promising treatment option as a innovative, more precise form of therapy.
Jędrzej Kowalski, Dominik Szymczak, Olaf Zołotar et al.· International Journal of Inn...· 0 citations
IBS is a complex medical condition, the usage of probiotics and other novel therapeutic agents may alleviate the severity of the disease and the understanding of the gut-brain axis as the basis of novel therapies shows promise in further implementation of more efficient treatment.
Joanna Kulpa, Kornelia Tyczka, Marcin Szczepanik et al.· International Journal of Inn...· 0 citations
Background: CAR-T cell therapy is a highly personalized form of treatment. it involves modifying T cells extracted from the patients white blood cells during cell collection. Genetic modification of said T cells allows for the extraction of chimeric antigen receptor (CAR), which are later multiplied and infused into th...
Kornelia Tyczka, Marcin Szczepanik, M. Nowakowska et al.· International Journal of Inn...· 0 citations
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