Marco Allinovi

Integrating the Urea-to-Creatinine Ratio with Clinical Variables to Improve Etiological Discrimination in Acute Kidney Injury

Background: The urea-to-creatinine ratio (UCR) is used to support the differential diagnosis of acute kidney injury (AKI); however, its diagnostic utility remains debated. We explored the clinical relevance of UCR in the initial etiological assessment of AKI, also considering relevant clinical modifiers. Methods: We re...

Extracorporeal Photopheresis as an Immunomodulatory Bridge in Kidney Transplant Recipients With Infections and Concomitant Donor-Specific Antibodies: A Case Series.

Kidney Biopsy and Prognosis in Lupus Nephritis: Histological Predictors of Renal Outcome—A Narrative Review

The kidney biopsy is the cornerstone of prognostication in lupus nephritis, yet which features predict renal outcome—and which kind—remains incompletely defined. This narrative review relates eight histological axes to two families of renal outcome defined a priori: soft outcomes (renal flare/relapse and response/remis...

Incidence and implications of anti-rituximab antibodies in nephropathies and other immune-mediated diseases: a narrative review

Rituximab is a chimeric anti-CD20 monoclonal antibody widely used in immune-mediated and hematologic diseases, but its efficacy may be limited by the development of anti-rituximab antibodies (ADAs). This narrative review summarizes current evidence on the incidence, detection, and clinical implications of ADAs in nephr...