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Author

Marco Bolis

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Open access Sep 2026

An integrated, transcript-resolution atlas of prostate cancer progression unmasks associations with oncogenic pathways

Most genes produce multiple non-coding and coding RNA transcripts with potentially divergent biological functions, yet their contribution to cancer remains largely unexplored. Here, we built an integrated, transcript-resolution RNA-sequencing atlas of prostate cancer spanning 1,140 clinical samples from 10 independent...

Ji-Chang Zhang, Claudio Lorenzi, D. Bossi et al. · 0 citations
Jul 2026

Abstract B014: Therapeutic Reversal of Tumor Cell Plasticity by EHF mRNA Delivery in Prostate Cancer

This strategy represents a first-in-class opportunity to target tumor plasticity and overcome resistance in advanced prostate cancer with a defined biomarker framework (low EHF expression, plasticity signatures) and compatibility with various delivery platforms.

D. Albino, C. Musumeci, Elisa Storelli et al. · 0 citations

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