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Author

Marco Reverenna

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Open access Sep 2026

Learning from tandem mass spectra at scale with a self-supervised foundation model for proteomics

InstaNovo-FM is presented, a self-supervised foundation model for bottom-up proteomics trained to reconstruct masked regions of tandem mass spectra and establishes a unified representation space for peptide fragmentation spectra, enabling robust transferability across the proteomics ecosystem.

M. Nieuwoudt, Marco Reverenna, Divanisha Patel et al. · 1 citation · ⚡1

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