CD8⁺ T cells infiltrate the brain parenchyma of patients with Alzheimer’s disease (AD), where they localize near microglia and neurons. Although recent studies have revealed that they can clonally expand and possess a unique phenotype, their contribution to disease pathogenesis remains poorly understood. To investi...
Marco Zattoni, Sabine Bernegger, H. Mrowetz et al.· Cellular and molecular neuro...· 0 citations
Alzheimer’s disease (AD), the most common age-related neurodegenerative disorder, is characterized by progressive synaptic and neuronal loss, amyloid-β deposition, hyperphosphorylated tau accumulation, and chronic neuroinflammation, traditionally attributed primarily to the innate immune system. Increasing evidence,...
Marco Zattoni, Ludwig Aigner· Molecular Neurodegeneration· 0 citations
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