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Marek Dzik

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Review Open access Aug 2026

Role of Sirtuins in the Pathogenesis of Osteoarthritis

Sirtuins (SIRTs) are a family of proteins involved in diverse cellular processes and play important roles in ageing and the development of osteoarthritis (OA). Among them, SIRT1, SIRT3, and SIRT6 have been identified as key regulators of cartilage homeostasis, primarily through their control of oxidative stress and mod...

Paweł Dec, Marek Dzik, Paulina Plewa et al. · 0 citations

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