From negative bone scintigraphy to oncologic superscan within five months: Explosive PSA kinetics in grade group 5 prostate adenocarcinoma
A 78-year-old man presented with a prostate-specific antigen (PSA) level of 35 ng/mL, a PI-RADS 5 lesion on multiparametric prostate MRI, and negative whole-body bone scintigraphy. Within five months, PSA increased to 1244 ng/mL despite minimal radiological progression of the primary tumour. Repeat MRI demonstrated mul...