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Author

Marek Michalak

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Jul 2026

Abstract B095: Targeted inhibition of SLC2A5 prevents tumour growth and metastasis

Two derivatives of a known GLUT5 inhibitor that prevent fructose transport in the micromolar to nanomolar range are identified using in-silico molecular docking and in vivo tumour xenograft experiments to determine the mechanism dictating essential fructose functions in cancer.

J. Groenendyk, K. Sahu, Lorne D. Tyrell et al. · 0 citations
Review Open access Jul 2026

The emerging roles of ITM2A: At the molecular crossroads of development and pathogenesis

This review systematically summarizes the complex regulatory mechanisms of ITM2A in growth, development, and disease, with a particular focus on skeletal development and tumorigenesis, aiming to provide a theoretical basis for its potential use as a biomarker for development and disease diagnosis/treatment, as well as...

Xiaoling Deng, Yi-Fang Wang, Lan Yang et al. · 0 citations

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