Margherita Doria

Identification of phenotypic abnormalities and effector function impairment in natural killer cells of patients with ataxia-telangiectasia

Ataxia-telangiectasia (A-T) is a rare inherited disorder resulting from mutations in the ATM gene and characterized by progressive neurodegeneration, immunological abnormalities, and increased infection and cancer susceptibility. There is no cure for A-T, and life expectancy is drastically reduced because of...