Human leukocyte antigen genotype modulates cytomegalovirus- and Epstein–Barr virus-specific T-cell response in healthy donors for optimized virus-specific T-cell donor selection
Introduction Reactivation of cytomegalovirus (CMV) and Epstein–Barr virus (EBV) is a major complication in immunocompromised patients, and understanding donor variability in antiviral immunity is essential for optimizing adoptive T-cell therapy. This study aimed to identify immunogenetic determinants of virus-specific...