Review
Open access
Oct 2026
A Systematic Review of Complement-Targeting Therapies for Geographic Atrophy: Insights into Advanced Drug Delivery Systems and Gene-Based Approaches
Background/Objectives: Geographic atrophy (GA), an advanced form of dry age-related macular degeneration (AMD), causes irreversible central vision loss and has limited treatment options. Complement dysregulation plays a pivotal role in GA pathogenesis. This systematic review synthesizes the efficacy, safety, tolerabili...
Paula Fernández-Muro, A. del Pozo-Rodríguez, María Ángeles Solinís et al.
· Pharmaceutics · 0 citations