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Maria Cruz-Santos

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Open access Aug 2026

Autism-relevant oxysterol signaling regulates GABAergic neurogenesis and interneuron subtype specification

It is shown that 24S,25-epoxycholesterol, an oxysterol enriched in the fetal brain and dysregulated in NDDs, enhances neurogenesis while altering the distribution of GABAergic neuronal subtypes, suggesting that aberrant oxysterol signaling contributes to the pathogenesis of NDDs.

Maria Cruz-Santos, E. Kidd, Zongze Li et al. · 0 citations